You’ve done it. After an exhaustive search, you’ve hired your first senior business executive—a brilliant, experienced leader poised to be your CEO, CPO, or CRO. They walk in on their first day, ready to build financial models, craft go-to-market strategies, and engage investors.
Meanwhile, your scientific team, the very core of your venture, continues their work, operating on a different clock, speaking a different language, and driven by the pursuit of discovery.
The moment these two worlds collide is one of the most dangerous and opportunity-rich inflection points in your company’s life. Without a deliberate plan, organizational antibodies can activate, leading to mistrust, miscommunication, and the creation of two separate, competing cultures under one roof.
Standard HR onboarding is not enough. You need a strategic, 90-day cultural integration mission. Its sole purpose is to build a bridge of trust, credibility, and shared understanding between your new executive and your founding scientific team. At DM & Associates, this is the framework we implement with our portfolio companies.
Phase 1: The First 30 Days - Deep Immersion & Earning Credibility
The goal for the first month is not for the executive to act, but to listen, learn, and absorb. Their first task is to earn the respect of the scientists, not by talking, but by demonstrating humility and a genuine desire to understand.
- Mandate a "Lab Coat Over Suit" Policy: The executive must spend at least 40% of their time physically or virtually alongside the science team. They should shadow technical meetings, observe experiments (where appropriate), and be a quiet presence where the real work happens.
- Assign a "Science Sherpa": Pair the new executive with a respected, patient member of your R&D team who can act as a guide and translator, helping them navigate the internal wiki and foundational research papers.
- Conduct a "Listening Tour": The executive must conduct structured, 30-minute, 1-on-1 meetings with every single member of the scientific and engineering team. The key questions aren't about business, but about their work:
- "What is the most exciting problem you are working on right now?"
- "What is the biggest obstacle to your progress?"
- "What do you wish the 'business side' of the company understood about your work?"
Phase 2: Days 31-60 - Mapping & Translating
With a foundation of earned trust, the executive now shifts from pure absorption to sense-making. Their goal is to begin building the bridge between the technology and the market.
- Create the "Bridge Document": The executive’s primary deliverable for this phase is a presentation that maps the current technical roadmap to potential commercial milestones and market opportunities. This forces them to synthesize what they’ve learned and articulate it strategically. This document is for internal discussion only.
- Execute a "First Small Win": The executive must identify one non-critical, operational bottleneck that has been frustrating the R&D team—slow procurement of lab equipment, a cumbersome software license process—and use their business acumen to solve it quickly. This demonstrates tangible value and builds immense goodwill.
- Facilitate the First "Science-for-Business Roundtable": The executive organizes and facilitates a meeting where a few scientists present their work to the founder and any other stakeholders, with the executive acting as the master translator, ensuring the commercial implications are clearly understood.
Phase 3: Days 61-90 - Aligning & Co-Creating
Now, and only now, can the executive begin to execute on their core mandate. With credibility established and the landscape mapped, they can shift to co-creating the path forward.
- Co-Create the Integrated Roadmap: Working as a partner to you and your technical leads, the executive facilitates the process of building the company’s first truly integrated Technology and Business Roadmap, using the "Bridge Document" as a starting point.
- Establish the Leadership Operating Cadence: The executive implements the formal meeting rhythms—the Weekly Vision Council, the Leadership Sync—that institutionalize communication between the scientific and business functions of the company.
- Deliver the 90-Day Plan: The executive presents their findings from the listening tour, their "Bridge Document," and the newly co-created integrated roadmap to you and the board. This presentation marks the official end of their onboarding and their transition into a fully operational leadership role.
This disciplined 90-day mission does more than onboard a person; it fuses two cultures. It builds a foundation of mutual respect and shared language that is essential for the long, arduous, and ultimately rewarding journey ahead.
A 90-day plan provides the framework, but successful integration requires consistent execution and clear metrics.
To ensure your new executive hits the ground running and to track their integration, DM & Associates has created a detailed "First 100 Days: Executive Integration Checklist & KPI Tracker." This practical tool includes:
- A week-by-week checklist of actionable tasks for the new executive.
- Template questions and a summary framework for the "Listening Tour."
- A sample KPI dashboard to measure the leading indicators of successful cultural integration.

